Centers & Services

Breast and Endocrine Surgery Department

What is the Breast and Endocrine Surgery Department?

This specialized department targets mammary gland, thyroid gland, and parathyroid diseases, conducting tests and providing treatments (including surgery and pharmacological therapies) in cooperation with other departments.

Our physicians

Director, Breast and Endocrine Surgery Department

Hiroyoshi Doihara, Professor
[Mammary / Breast surgery / Endocrine surgery]


Junji Matsuoka Professor [Palliative support medical care]
Naruto Taira Associate professor [Mammary/Breast surgery /Endocrine surgery]
Tadahiko Shien Assistant professor [Breast surgery /Endocrine surgery]
Hirokuni Ikeda Assistant professor [Mammary/Breast surgery /Endocrine surgery]
Taeko Mizoo Part time lecturer [Mammary/Breast surgery /Endocrine surgery]
Takayuki Iwamoto Assistant professor [Mammary/Breast surgery /Endocrine surgery]
Yuko Abe Resident [Mammary/Breast surgery /Endocrine surgery]
Mariko Kochi   [Mammary/Breast surgery /Endocrine surgery]
Maya Uno   [Mammary/Breast surgery /Endocrine surgery]
Keiko Nishiyama   [Mammary/Breast surgery /Endocrine surgery]
Minami Hatono   [Mammary/Breast surgery /Endocrine surgery]
Kengo Kawada   [Mammary/Breast surgery /Endocrine surgery]
Yuko Takahashi   [Mammary/Breast surgery /Endocrine surgery]
Ryo Yoshioka   [Mammary/Breast surgery /Endocrine surgery]
Takahiro Tsukioki   [Mammary/Breast surgery /Endocrine surgery]

*Specialty shown in [ ]

Outpatient clinic physicians

Monday Tuseday Wednesday Thursday Friday
Outpatient physicians Morning Professor Matsuoka Clinical fellow Kochi Assistant professor Iwamoto Professor Doihara Assistant professor Shien Assistant professor Ikeda Professor Matsuoka Associate professor Taira Professor Doihara Assistant professor Shien Lecturer Mizoo Associate professor Taira Assistant professor Ikeda
Afternoon   Professor Doihara (Young, familial breast cancer outpatient) Associate professor Taira Assistant professor Shien Assistant professor Ikeda Associate professor Taira Professor Doihara (Young, familial breast cancer outpatient) Assistant Professor Shien Associate professor Taira

Treatment system


Junji Matsuoka (professor of the Palliative Support Medical Care Department, Naruto Taira (physician, mammary gland specialist), Tadahiko Shien (physician, mammary gland specialist, Endocrine surgery specialist), Takayuki Iwamoto(physician, mammary gland specialist), Taeko Mizoo (physicians, mammary gland specialists), Hirokuni Ikeda, Mariko Kochi

Treatment policy

  • Breast cancers: in terms of surgical treatments, we choose between mastectomy and breast-conserving surgery according to the degree of disease progression and a patient’s wishes. We can offer different types of breast reconstructive surgery in cooperation with the Department of Plastic Surgery. Regarding pharmacological therapy, we provide evidence-based standard treatments.
  • Thyroid and parathyroid diseases: in addition to standard surgeries, we can also offer small incisions for cosmetic reasons depending on the circumstances.


Our department is an institute certified by the Japanese Breast Cancer Society, providing world-standard treatment and education for a university hospital to face anticipatory research and to train specialists. Additionally, we perform team medical care with nurses and pharmacists. In breast cancer surgeries, the time has come when not only curative effects but also cosmetic effects are considered. Our department has also established the Breast Cancer Treatment and Reconstruction Center collaborating with the Department of Plastic Surgery so that we can perform high-quality breast reconstruction surgeries at the first stage aside from breast conservation surgeries.

Scope of target diseases

  • Mammary gland diseases
    Breast cancer
    Mammary benign tumor
  • Thyroid diseases
    Thyroid cancer
    Thyroid benign tumor
    Hyperthyroidism, Grave’s disease
  • Parathyroid diseases
    Primary hyperparathyroidism
    Secondary hyperparathyroidism


  • The Endocrine Center (established September, 2006) is managed for more functional diagnosis, research, and education of endocrine diseases, especially thyroid diseases, in cooperation with the Department of Endocrinology by abolishing the boundaries separating conventional therapies by department. The number of cases the center deals with is among the largest in the Chugoku and Shikoku districts.
  • Breast Cancer Treatment and Reconstruction Center (established April, 2008): A team of specialists including health-care providers has been assembled to offer complete breast cancer team medicine. Full partnership of the Department of Plastic Surgery particularly enables our department to offer top-class breast reconstruction as well as top-class breast cancer treatment in Japan.
  • Specialists and nurses specializing in mammary gland diseases collaborate with fertility specialists and reproductive psychological counselors to provide female function counseling support for patients with breast cancer who are receiving drug therapy.
    This approach has been initiated as a group study of the Japanese Breast Cancer Society, which is at the frontier of treatment in Japan.
  • Setouchi Breast Project Comprehensive Support Organization (established September, 2009): The organization contributes to the development of local medical care and health maintenance and the enhancement of quality of life by supporting breast cancer-related activities performed in the Chugoku and Shikoku districts.

Description of medical care

[About breast diseases]

Today, Okayama University Hospital is an institution certified by the Japanese Breast Cancer Society. We have studied mainly surgical treatments and recurrent breast cancer treatments in clinical practice, elucidation of new prognosis factors, mechanism of molecule target therapy and anticancer drugs, and tolerance of hormone drugs in basic study. Herein, we introduce surgical treatments and recurrent breast cancer treatments.

<Breast conserving surgery>

The mainstream of current breast cancer surgery includes pectoral conservation mastectomy and breast conserving surgery. The latter is likely to have increased recently. Since 2000, 70% of the patients of this department have undergone such surgery. We conduct breast conserving surgeries on all cases with a tumor having 3 cm or smaller diameter; for patients with a tumor larger than 3 cm diameter, we provide preoperative anti-cancer drug treatment and then perform breast reconstruction after the tumor diminishes, striving to perform conserving surgery whenever possible.

<Sentinel lymph-node biopsy>

entinel lymph-node
Biopsy intraoperative photographs
Arrows in the figure: stained
Lymphatic vessel and lymph node

Sentinel lymph-nodes, the first lymph-nodes that lymph flow reaches, have become detectable to an increasing degree recently. Breast cancer cells presumably metastasize to the sentinel lymph-node with the lymph flow first. Consequently, if one can ascertain whether metastasis has occurred or not to the sentinel lymph-node, one can know the whole state of axillary lymph node and also avert lymph node dissection in a patient without metastasis to the lymph node. This department has introduced sentinel lymph-node biopsy, striving to reduce complications such as edema in upper limbs and nerve damage caused by dissection.

<Treatments for Metastatic Breast Cancer>

Endocrine therapy, anticancer drug treatment, radiation therapy, and recently molecularly targeted drugs such as Herceptin, Tykerb, Perjeta and Cadcyla are certified as treatments for recurrent breast cancers. It is now impossible to cure recurrent breast cancers. Therefore, our treatments are designed to extend the survival period and to provide better quality of life.

[About thyroid diseases]

Our department, at which the head office of the Chugoku and Shikoku Districts' Society of Thyroid Surgery is placed, has performed numerous surgeries for thyroid diseases.

Highly advanced/specialized medical treatment

Techniques performed as medical treatments at a patient's own expense

  • Radiofrequency ablation (RFA) for early stage breast cancer (Advanced medical care B)
  • Genetic diagnosis
  • Fertility conservation therapy for patients undergoing drug therapy for breast cancer

Main methods for testing and explanation

Tests we can perform

  • Ultrasonography
  • Mammography (certified by Japan Central Organization on Quality Assurance of Breast Cancer Screening)
  • MammotomeR biopsy
  • VacoraR biopsy
  • MD-CT, MRI
  • Breast ductal endoscopy
  • Different RI examinations

Main testing methods and medical equipment

Ultrasonography, mammography, cytodiagnosis, core needle biopsy, breast CT (MD-CT), breast MRI, breast ductal imaging, breast ductal endoscopy, nuclear medical study, intraoperative rapid pathology, MammotomeR biopsy, and VacoraR biopsy